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✉news ScienceBiology first seen 5 h ago, last 1 h ago, peak #37

Optimized lipid nanoparticles boost in vivo genome editing

Original: Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing

Researchers report lipid nanoparticles engineered to carry large RNA payloads and target specific tissues can enhance genome editing directly inside living organisms. The work, published in Nature, addresses a key limitation of delivery vehicles in gene editing by improving both cargo capacity and tissue selectivity. Scientists say such delivery advances could broaden the range of diseases treatable with in vivo gene therapies.

Why now: A new Nature paper shows a delivery technology improvement that could expand the practical use of genome editing therapies.

Naturelipid nanoparticlesgenome editing

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