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genome editing
Trends
- 1Woolly mammoth to be resurrected with the help of AI, scientists say▼Woolly mammoth to be resurrected with the help of AI: scientists
Scientists say artificial intelligence could help bring the woolly mammoth back from extinction, according to a report. AI is being used to analyze the mammoth genome and accelerate efforts to edit elephant DNA so the Ice Age giant's traits could be recreated. The idea of de-extincting the mammoth has drawn both excitement and skepticism about whether such a creature can truly be brought back.
- 2Optimized lipid nanoparticles boost in vivo genome editing●Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing
Researchers report lipid nanoparticles engineered to carry large RNA payloads and target specific tissues, improving genome editing directly inside living organisms. Published in Nature, the work addresses a key limitation of delivery systems for gene-editing therapies. Scientists say better tissue targeting could broaden the range of diseases treatable with in vivo editing, moving the field closer to practical, non-viral therapeutic delivery.
- 3CRISPR-Edited Plants Need a Sustainable Innovation System▼CRISPR Beyond the Lab: Why Genome-Edited Plants Need a Sustainable Innovation System
Commentary argues that CRISPR genome-edited plants must move beyond laboratory success into a broader sustainable innovation system covering regulation, farming practice and commercialisation. The piece stresses that editing crops is only one step; lasting impact depends on infrastructure, policy and responsible deployment in agriculture.
- 4Study maps rational selection of adenine base editors for human genome editing●Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing
A Nature publication describes a rational framework for choosing between SpCas9 and variant-derived adenine base editors when editing the human genome. The work aims to help researchers match editor choice to specific target sites and desired edits, improving precision in gene-editing applications. The paper is being circulated among readers following advances in CRISPR-based genome editing tools.