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human genome
Trends
- 1Jumping human gene discovered inside a virus●A human gene that can jump has been found inside a virus
Researchers report the discovery of a human 'jumping gene' — a transposable element able to move around the genome — found embedded inside a virus. The finding suggests genetic material can move between humans and viruses, shedding light on how genomes evolve and how viruses may acquire host genes. Scientists say it could inform understanding of gene transfer and viral evolution.
- 2Study maps rational selection of adenine base editors for human genome editing●Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing
A Nature publication describes a rational framework for choosing between SpCas9 and variant-derived adenine base editors when editing the human genome. The work aims to help researchers match editor choice to specific target sites and desired edits, improving precision in gene-editing applications. The paper is being circulated among readers following advances in CRISPR-based genome editing tools.
- 3New Tool Decodes Ancient Viral Fossils in Human Genome▼Ancient Viral Fossils Decoded: New Tool untangles the Human Genome’s Endogenous Retroviruses
Researchers have unveiled a new computational tool that disentangles endogenous retroviruses, the remnants of ancient viral infections embedded in human DNA. These 'viral fossils' make up a large share of the genome and have been linked to gene regulation, development and disease. The tool promises clearer mapping of these sequences, a step forward for genomics and evolutionary biology.